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Insufficient of Nutrients Leads Depression
- Low Level of Folate is Common in Depressive Patients
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Low Level of Vitamin B12 is Also Common in Depressive Patients
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How Do Folate and Vitamin B12 Relate to Depression?
- Both Folate and Vitamin B12 are necessary to synthesis S-adenosylmethionine (SAM), which is able to reduce the symptoms of depression.
- The depressive patients who are the deficiency of both Folate and Vitamin B12 are also lower cerebrospinal fluid (CSF). Lower CSF indicates disturbances in serotonin, dopamine and noradrenaline turnover.
- The deficiency of Folate and Vitamin B12 increases the level of homocysteine which causes cerebrovascular disease, monoamine neurotransmitters, and depression of mood.